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Flow simulation in the Aventis E-Haler drug delivery device.
Application: CFD Optimization of Inhaled Therapies
Posted Thu September 25, 2003 @01:36PM
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Application By Keith McCormack,
Department of Medical Physics, University of Sheffield, UK
and Ian Jones,

Using state-of-the-art modeling techniques, COPHIT software simulates the entire dynamic drug delivery process for particulate, aerosol and gaseous drug types, from the device, through the lungs to the pulmonary system. The software is designed for use by pharmaceutical companies and clinicians who need to predict and optimize inhaled therapies, and allows deposition and uptake to be customized for particular drugs, delivery devices, diseases and even individual patients. It has been developed within COPHIT, which is a project part-funded by the Commission of the European Communities.

The software is the first known implementation of a fully-coupled 1-D/3-D model of the complete pulmonary drug delivery process.

( Read Full Article )

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